Welcome

Open source tools

Silicos-it contributes its expertise to the chemoinformatics community by porting its source code into the open source domain. Famous examples include our spectrophore descriptors, the filtering program Filter-it™ and the pharmacophore tool Align-it™. Information and downloads of all our open source programs are found in the tools section of this site.

Sharing information

This site has been developed to share information on open source chemoinformatics and how it can help you in your daily work. For this purpose, our blog provides tips on working with molecular toolkits, shares known problems and gives insight in some of our learning experiences. In addition, the molspace section gives you some background on our large collection of vendor compounds that we maintain to support our clients with a variety of chemoinformatics solutions. Finally, the links section provides access to other sites in the chemoinformatics arena that we find interesting enough to share with you.

Customers and partners

Over the years, Silicos-it has build up an extensive customer base, ranging from ✓ pharmaceutical companies to identify new inhibitors against difficult pharmacological targets, ✓ biotechnology companies to find leads using docking technologies and pharmacophore alignments, ✓ startup companies that need molecular modeling expertise to support their lead optimization efforts, and ✓ academic groups that want to setup an internal database system for compound storage, clustering and selection. And in order to bring to our customers an even wider range of IT-support, we have setup extensive partnerships with Altran and Emweb.

We hope that this website encourages you to contact us to discuss potential collaborative work.